The Open University ’ s repository of research publications and other research outputs Postmitotic neurons develop a p 21 - dependent senescence - like phenotype driven by a DNA damage response

The Open University ’ s repository of research publications and other research outputs Postmitotic neurons develop a p 21 - dependent senescence - like phenotype driven by a DNA damage

The Open University's repository of research publications and other research outputs Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response Journal Article (2012). Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Copyright and Moral Rights for the articles on this site are retained by the indivi...

’ s repository of research publications and other research outputs Postmitotic neurons develop a p 21 - dependent senescence - like phenotype driven by a DNA damage

The Open University's repository of research publications and other research outputs Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response Journal Article (2012). Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Copyright and Moral Rights for the articles on this site are retained by the indivi...

publications and other research outputs Postmitotic neurons develop a p 21 - dependent senescence - like phenotype driven by a DNA damage

The Open University's repository of research publications and other research outputs Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response Journal Article (2012). Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Copyright and Moral Rights for the articles on this site are retained by the indivi...

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

In senescent cells, a DNA damage response drives not only irreversible loss of replicative capacity but also production and secretion of reactive oxygen species (ROS) and bioactive peptides including pro-inflammatory cytokines. This makes senescent cells a potential cause of tissue functional decline in aging. To our knowledge, we show here for the first time evidence suggesting that DNA damage...

The Open University ’ s repository of research publications and other research outputs Gamma radiation damage study of 0 . 18 m process